The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

本研究系统揭示了DNA双链断裂修复后的一个被长期忽视的层面：染色质结构与基因功能的不可逆改变。这种结构性与功能性损伤可稳定地传递给子代细胞，形成一种可遗传的基因表达缺陷，被作者定义为“染色质疲劳（chromatin ...

After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...

A breakthrough live-cell sensor makes DNA repair visible as it happens, unlocking new possibilities in biology and medicine.

In a quiet lab at Utrecht University, researchers have built a tool that lets you watch one of life’s most serious crises ...

Cedars-Sinai scientists have developed an experimental drug that repairs DNA and serves as a prototype for a new class of ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

Learn about the innovative fluorescent sensor technology that visualizes DNA damage and repair in real time, enhancing medical research.

New live-cell DNA damage sensor lets scientists watch repair unfold in real time, potentially opening doors for cancer and aging research.

Cedars-Sinai researchers have created TY1, an experimental RNA-based drug that helps the body repair damaged DNA and restore injured tissue. The idea came from studying tiny molecular “messages” ...

Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing ...

我们细胞中的DNA，无时无刻都在遭受来自阳光、化学物质、辐射，以及维持生命活动的各种生物过程的损伤，这些损伤会威胁基因组的完整性和正常功能。通常，细胞能快速且高效地修复这些损伤，但当修复能力下降时，后果就可能十分严重，甚至能导致衰老、癌症，以及多种疾 ...