Cytochrome P450 enzymes constitute a superfamily of haem-containing proteins that catalyse the oxidation of a wide range of exogenous and endogenous compounds. Their function is fundamental to the ...

Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely used to treat a range of infections, including pneumonia and skin ...

A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction in ...

Focusing on an enzyme in yeast, they demonstrated how contrasts in atomic scale motions impact their function. The method promises unprecedented access to the mechanisms by which biomolecules work, ...

Scientists at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have captured real-time images showing how ...

While E. coli is one of the most studied organisms, the function of 30% of proteins that make up E. coli has not yet been clearly revealed. For this, an artificial intelligence was used to discover ...

Enzymes originally evolved in high-temperature environments and later adapted to lower temperatures as Earth cooled. Scientists discovered that a key shift in enzyme function occurred over ...

A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...

Sam Pellock receives funding from the Washington Research Foundation and Schmidt Sciences. Enzymes are molecular machines that carry out the chemical reactions that sustain all life, an ability that ...

The human body undergoes numerous changes throughout life, with many significant transitions occurring during the decade of the 40s. Among these changes, the decrease in digestive enzyme production ...