To our knowledge, this analysis is the largest EHR-based study for identifying drug repurposing candidates for ALS. We identified several drugs that warrant further assessment as therapeutic options ...

Objective To synthesise the evidence on the effects of physical activity on symptoms of depression, anxiety and psychological distress in adult populations. Design Umbrella review. Data sources Twelve ...

Objective To investigate the association of running participation and the dose of running with the risk of all-cause, cardiovascular and cancer mortality. Design Systematic review and meta-analysis.