Genetic disorders occur due to alterations in the primary genetic material—deoxyribonucleic acid (DNA)—of an organism.

Researchers uncovered a previously unknown CRISPR immune response in bacteria that targets transfer RNAs. The newly identified nuclease Cas12a3 precisely cuts the conserved tRNA tail, halting protein ...

Scientists are testing CRISPR gene editing as a potential HIV cure after successfully removing the virus from infected cells ...

Scientists have discovered a new CRISPR mechanism with precise activity, expanding the potential applications of the existing CRISPR toolbox.

The AHA recommended whole exome or whole genome sequencing as first-line diagnostic tools for mitochondrial diseases.

CRISPR–Cas9-based therapies are widely investigated for their clinical applications. However, there are limitations ...

本研究针对CRISPR-Cas系统在微生物基因交换中的双重作用机制这一科学问题，开展了CRISPR-Cas靶向对嗜盐古菌Haloferax volcanii种内接合影响的主题研究。研究人员通过精确的基因编辑构建靶向菌株，结合接合实验、Cas3基因敲除和DNA损伤处理等实验，发现CRISPR-Cas靶向可 ...

Researchers from Würzburg, Braunschweig, and the US identifiy Cas12a3 nuclease showing precise activity. Their study is published in Nature ...

Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism.

Plus: Grok is restricting its image-generating function to paid subscribers only This is today's edition of The Download, our weekday newsletter that provides a daily dose of what's going on in the ...