Cilia are evolutionarily conserved, microtubule-based organelles that project from the surface of most eukaryotic cells and play a central role in sensing ...
Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder. Ali Ghoochani, Julia C. Heiby, Eshaan S. Rawat, Uche N. Medoh, Domenico Di Fraia, ...
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New findings explain how lysosomal defects trigger neuronal energy failure
Together with colleagues from Stanford University, USA, researchers at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) have, for the first time, created a comprehensive cell ...
The mini review brings together emerging evidence showing that glial cells actively influence disease progression and ...
Modern cells are complex chemical entities with cytoskeletons, finely regulated internal and external molecules, and genetic ...
Researchers have developed a way to 3D print custom micrometer-sized structures directly into the interior of living cells.
Dewpoint has selected a novel small molecule to prevent the formation of abnormal TDP-43 protein clumps in ALS and other ...
The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...
Exosome-associated THSD7A is identified as a key trigger of filopodia formation in cancer cells and neurons, revealing a ...
Researchers have harnessed AI to expedite the creation of lightbulb-like intrabody probes that can track activity in living ...
A selective protein degradation system known as Golgi membrane-associated degradation (GOMED), which identifies and removes ...
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