本研究针对合成基因回路在进化压力下易失活的问题,通过结合计算模型与体内诱变实验,揭示了质粒拷贝数(PCN)与调控架构如何协同影响表型突变率。研究发现,高PCN虽能促进功能获得性突变,但会抑制功能丧失性突变;同时,调控区突变比编码区突变更易在 ...
Access to treatment for leprosy is essential to global efforts to eliminate leprosy, says the World Health Organization (WHO) ahead of World Leprosy Day, to be observed on 25 January. Leprosy is an ...
What better time to contemplate the conundrum that is zero than the start of a new year? Zero is a fairly new concept in human history and even more recent as a number. It wasn't until around the 7th ...