A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as a kind of "traffic controller" on DNA. Without this protein, chaos ensues, ...

CDT1 inhibits the helicase activity of the MCM complex, thereby suppressing nascent strand synthesis in DNA replication in cultured human cells. This action results in fork collapse and DNA damage, ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...

The Age of AI will rely on massive volumes of data that can be easily stored and retrieved—and bioscience may have an ingenious solution. A scientist examines a DNA (deoxyribonucleic acid) profile on ...

Retro cassette tapes may be making a comeback, with a DNA twist. While DNA has been used as an information storage medium before, researchers have now combined this with the convenience and look of a ...

DNA, deoxyribonucleic acid, carrying encoded genetic information at molecular level, is the most significant discovery in the history of genetics. Previous researches on DNA included topics of bases, ...

A new study shows that DNA forms coils under stress, not the tangled knots that scientists expected. When you purchase through links on our site, we may earn an affiliate commission. Here’s how it ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

Genetic genealogy is identifying the mothers of deceased newborns found abandoned, shedding light on crimes that went unsolved for years. Women now may face lengthy prison sentences for decades-old ...

Ensuring that DNA replication occurs at the right stage of the cell cycle is of crucial importance in biology. In bacteria, DNA replication begins with the assembly of a DNA-protein complex called the ...